Hi Rever27,
Please note that we unfortunately don’t assist trouble-shoot specific EAs. In your case, you will need to compare what the differences there are in the buy/sell triggers of your EA that could cause this. Check an individual trade and compare it to see why there are differences. When working in the H4 timeframe, it is unlikely that it’s tick data that’s causing the issue unless your EA is sensitive to spread and/or is a scalper. In the first instance, I would be comparing the H4 open/high/low/close and whatever parameters that cause the EA to trigger.
Regarding what TF to use when testing multi-timeframe advisors, this would depend on how the EA is coded and is best answered by the vendor.
Hope this helps.